2025 Summer Intern – Structural Biology (roche)

Job Description

2025 Summer Intern – Structural Biology

Department Summary

The Department of Structural Biology is a world-leading research and drug discovery organization focusing on cutting-edge biomedical questions. We pursue challenging and important problems that aim to uncover fundamental biological mechanisms that would advance our understanding of human physiology in health and disease. We are fully equipped with state-of-the-art facilities, including cryo-electron microscopy (cryoEM) suite with two Titan Krios electron microscopes, Glacios electron microscope, and other equipment that is readily available and accessible for use during the internship.JOB IS FROM: nursingjobs.siteVIEW

This internship position is located in South San Francisco, on-site.

The Opportunity

We are seeking a motivated scientist interested in using structural biology to understand the molecular mechanism of action of large macromolecular complexes involved in DNA repair processes. The internship involves protein purification, reconstitution, and structure determination of DNA-protein complexes using cryoEM. Additionally, you would help us develop functional biochemical assays to assess and determine the mechanism of action of various multi-subunit protein complexes. You will be highly encouraged to think deeply about the biological problem, make significant intellectual contributions to the chosen research project, and work closely with other team members.

Program Highlights

• Intensive 12-weeks, full-time (40 hours per week) paid internship.

• Program start dates are in May/June 2025.

• A stipend, based on location, will be provided to help alleviate costs associated with the internship.

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Who You Are (Required)

Required Education

• Must be pursuing a PhD (enrolled student)

Required Majors: Structural biology, Biochemistry, Molecular Biology, Biophysics, Cell biology.

Required Skills:

• Proficiency in basic biochemical techniques.

• Experience with protein purification.

• Critical thinking.

Preferred Knowledge, Skills, and Qualifications

• Basic experience with cryoEM sample preparation and data processing.

• Experience with DNA-protein complexes biochemistry or biophysics.

• Communication, collaboration, and interpersonal skills.

• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $45.00 per hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

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Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.