Job Description

2025 Summer Intern - gRED, Regev Lab

The Opportunity

Prostate cancer is the most commonly diagnosed cancer in men. As resistance emerges in late-stage castration resistant prostate cancer, malignant cells often trans-differentiate from an epithelial to a neuroendocrine lineage. Treatment options for patients with neuroendocrine prostate cancer (NEPC) are limited due to its aggressive nature and a rudimentary understanding of the disease. Novel immunotherapies have also been largely unsuccessful in NEPC patients. The Regev lab has engineered a mouse model that recapitulates all stages of the disease, with knock-in model neoantigens to allow neoantigen-dependent CD8 and CD4 T cell infiltration. Based on single cell and spatial transcriptomics data collected from this system, we would like to understand the mechanism by which tumor resident and infiltrating immune cells influence the trajectory of neuroendocrine differentiation. 

This internship position is located in South San Francisco, on site.  

Program Highlights

• Full time for at least first 12 weeks (40 hours per week) paid internship.

• Program start dates are in July (Summer), approximately.

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• A stipend, based on location, will be provided to help alleviate costs associated with the internship. 

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Required Education

You meet one of the following criteria:

- Must be pursuing a PhD Degree (enrolled student)

Required Majors

Biological & Computational Sciences

Required Skills

Ability to lead and design the computational analysis to address the biological questions.

Preferred Qualifications

• Experience with analysis of single cell data. 

• Familiarity with state-of-the art tools.

• Knowledge and experience with deep learning frameworks.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location for this position in California is $50.00 per hour.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.