Medicinal Chemistry Intern (neurocrine)

neurocrine    US CA San Diego    2024-12-21

Job posting number: #167307 (Ref:R5217)

Job Description

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

What We Do:

Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company’s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson’s disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science.

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*in collaboration with AbbVie

About the Role:

Neurocrine Biosciences, Inc. (NASDAQ: NBIX) is offering the opportunity to gain research experience in Medicinal Chemistry at our laboratories. Our intern program offers exposure to the chemistry behind our efforts at discovering new compounds and advancing them within our pipeline. This role offers the participant both theoretical principles about medicinal chemistry as well as important practical aspects such as automation and synthesis.

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Your Contributions (include, but are not limited to):

  • Synthesizing novel chemical intermediates and final compounds

  • Reviewing the chemical literature to obtain procedures, guide reaction sequences 

  • Setting up, monitoring by TLC and/or LCMS, and working-up reactions 

  • Purifying compounds by automated chromatography (ISCO combi-flash or ACCQprep) or recrystallization 

  • Learning about and applying medicinal chemistry and CNS-drug discovery principles to drug discovery projects 

  • Generating and interpreting biological data 

  • Helping develop plans to address medicinal chemistry goals 

  • Maintaining a complete laboratory notebook 

  • Interacting with other chemists and pharmacologists within the company 

  • Completing a special project and present the recommendations to management upon completion 

Requirements:

  • Candidate must be enrolled in a graduate degree program in one of the following areas: Organic Chemistry or Medicinal Chemistry 

  • Practical experience with organic synthesis, methods development, total synthesis, or similar 

  • Ability to work in a laboratory environment 

  • Prior laboratory experience (Minimum>1 year) 

  • Good verbal and written communication skills  

  • Ability to think creatively and be a team player  

  • Interest in attending various program events, including social gatherings, career development workshops, and more 

  • Ability to commit to a 10-12 week full-time summer program 

#LI-TM1

Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.



Employer Info

Job posting number:#167307 (Ref:R5217)
Application Deadline:2025-01-20
Employer Location:neurocrine
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