Research Technician - Johnstone Lab (Danafarber)

A research technician position is open to join the Johnstone laboratory in the Department of Pathology at Dana-Farber Cancer Institute. Dr. Johnstone studies how DNA is packaged within the nucleus of cancer cells and how alterations of packaging impact transcriptional programs and tumor cell biology. It has long been characterized that the nuclei of cancer cells look atypical by histology, and this feature is used by pathologists for the accurate diagnosis of malignancy. We aim to more fully characterize the molecular mechanisms underlying this phenomenon, specifically focused on how the DNA fiber is topologically and epigenetically organized within the nucleus and how cancer-specific changes to this organization relate to tumor morphology and impact tumor cell state.  We use engineered tumor models, advanced genomics techniques and high-resolution imaging approaches to probe genome topology and chromatin state.

 

The successful candidate is a highly-motivated, bachelor’s level graduate strong academics. He/she will contribute a culture of intellectual rigor, joyful scientific discovery and collaboration.  He/she will work closely with Dr. Johnstone to lead a project focused on defining oncogene amplification and genomic structure in sarcoma.  The candidate will help lead priority research and contribute to novel directions for the laboratory. 

 

The ideal candidate is an eager learner and seeking a dynamic research environment in which they can advance their scientific and research skills.  Dr. Johnstone is committed to the training and support of the candidate.  This includes career mentoring and education training if this fits the candidate’s long-term interests. Dr. Johnstone will be available to advise candidates on future education plans, to include graduate or medical school. We are seeking candidates with at least two years of availability.  A collaborative, positive and enthusiastic scientist will flourish in the lab and be very supported in their future ambitions.

 

Please provide a cover letter with a description of your previous research, reasons for wanting to pursue research in the Johnstone laboratory and a copy of your CV with your undergraduate GPA. Three references will be required if selected for an interview. JOB IS FROM: nursingjobs.siteVIEW

 

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Responsibilities will include:

 

• Execute and troubleshoot experiments to include next-generation sequencing and cell culture and manipulation
• Document experimental protocols and results
• Interpret and analyze data in collaboration with lab members and the principal investigator
• Order supplies and prepare common lab reagents
• The candidate will interact with a diverse group of scientists, physicians and administrators so excellent communication skills are required- both written and oral
• Attention to detail and fastidious technical skills and record-keeping are essential

Qualifications:

• • A Bachelor's degree, preferably with a major in molecular biology, cell biology or genetics.
  • Previous experience in a research lab is strongly preferred.
  • Strong foundational skills in biochemistry and experimental biology (through research experience or classroom teaching) is ideal.
  • Prior experience programming in R or Python or interest in learning basic programming is a plus.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

 

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

 

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